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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d2cde53654d887b6d01ac8986526e0dc23c688bb0e4c552e18852d319f900d' 
  AND token = 'NhXbESc5eHF26lYwEwTUkNnvIaEOxKf9+gHkQifNflI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}