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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c37f426083015990ecfc68aeed003c6f5e86a1725247d7a635c52abeac6728d' 
  AND token = 'QilAjHfDC6eINXrikraZ+JBWM/xJmCERZ6JJns1ZRQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}