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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f81382867531fc215e6de3f3013e5c23855a166c831060a93445a9849bc46ea7' 
  AND token = '2GoYTywulHEZrEJHsER7QkRXP0LX7qh/TjrjTpbHp5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}