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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e4cb365e771573e5c5124dc34877f10cd2c2f44085f3b9672c4edd4b3c5b69' 
  AND token = 'kct6e/M/T0S2gsf1Nx/LrErEuP58XjynG1UabVaHPSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}