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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c898bc5d6fd73bb6121c7e21354fc43bd6be594e0273e56fa7c5846f14a37be' 
  AND token = 'DHrWV9mEUBfx3c1/XBblOl7L/B1TMGueT6yOQRugbak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}