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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e42a8283f17b625703f9dacf10a2989f8434ff2d71b7339763fd78891b77094' 
  AND token = 'x4UUWjH10bxOqAD/O+xbe2My+Z/85a9EEepR+XcFswc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}