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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a7d6c265ceee5f4dd490bc8bcc1f12f9eaf377e49a7c80b5949495887f09fd4' 
  AND token = 'XcBqQNJr25Mxz0yCLTDgyEYPq030k4Sm7EI6l24k7SI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}