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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9a909f5b3fded3b7f618c125cfad90fef97d7a36268e1c53a1726f715e3a5c5' 
  AND token = '/gA13e9DeJsl+e9Iiwtu7FMeKlIfBrgzEN8ypKPmlN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}