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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '667c85606db0bc4914729d2123f1b51d516b9b57b2ccc58c378609b058e17b48' 
  AND token = 's7tF5QMqJ0bGtGA0cLX/52LV88lA9SOp6HMyWOsspw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}