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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '333c47ef49377860fb4120afaab17c32a7b8bcf98af1f16d9c6e587943046374' 
  AND token = 'po4oX23ZN2eLDcQ+gBoqPT86Khy+tO0Zv5b+R7QHZXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}