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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b689a5b9429975b0a71169838cac31352ac4c97cf0a927907ea81fca1c0d0c2' 
  AND token = '8Dt/TzFzYnw/VAtVBBK6Y46I2/m9UxL8p8AIJt2K0k8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}