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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1e35eed490a52582ca4bd5490e172b0f38ec5003c5c8a666ab38728bf3c9736' 
  AND token = 'RG/8KjDbgv8B8r4AMRtzU8isNvpYogtNjvEfeTdcJX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}