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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e82a3053bac3f3f4fda502aa96d5fb3cf70e7e31337f5c48231c9409de0a6c' 
  AND token = 'r1UuplEgoHbcmW1YeoVkSCoYHYezvFwjeDTtsvEGZ9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}