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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd86bb50d467728777f28fe3442d026418c6b819c04a2c2d7e4d5b38503c681b' 
  AND token = 'sG85n+cZkqqU+xqwD5Dcxd/T4NgDKeI1k69ZmnaDQdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}