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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d366e5f86e98adb95a812f2b10a4770d7f9fd4dd6f4bdea4dd81a47c10e02ac' 
  AND token = '5F/0VTCVeTGhexK7D/iFz3s+ypH6DjKnFxr9jCRZRb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}