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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1065c840fb74f826304d83459f3c8ee1a0ef84e8d6b789fd30b010c5863227' 
  AND token = '9r5+qqWm6wv6OePrhocq0Cz5M11X5vl15Hl/FvBtHdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}