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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2840a717fce113a453678e7b5a3d0af4192bd093059d0cc3acd2d44a2ea036' 
  AND token = 'FNxG2td8yL6jRzjkHkctlGzRYrlDukR6/fhmGY/0Io0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}