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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44421d7c46f5037267ad40662d622d8d7accc20d6b1066ee7b0e6a7476dc5d47' 
  AND token = 'DpNsZ4rGdXbhjcB5gdT0/1mGI0OQSuNqjQm/CPqFq5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}