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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43efd17bb320c835053d4c7308148379606f1f5b97961f9c5e8d124da8cdcd9' 
  AND token = 'RSAjnbktnmOvnIIZrugknEDeJoirS6IChl+I09kLww0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}