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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c0a8f9e9b8252f1e6549c5d11389848332b92866309d5bca479f8263bdfa04' 
  AND token = '8PkgRMhX2Bcpao/l3EXm+8HJRJ6f1PRjCxe4BBB1gTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}