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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bc2d18f90997303596f3f1c33e5c21da48ae7ab7e8ceb0a31b501c024bc4621' 
  AND token = 'AGD0itpPGCKdTfKiH2qW0QqXPdezJ8uWVF+koA3Vpfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}