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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79bde59b13f87a6cba623f1f06f1a23b35272886c32aeb6a76606465072bc998' 
  AND token = 'E5fIFPJtaNQP1L1d26i1VLaDVUNG5d5UQmH+LCG4li8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}