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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4add08895c127e4b954f888d0d609c1d5b2279519cc21b75f53c164e789e0468' 
  AND token = 'NrBPrZ8xq8Cn/t4PKEfad95DSiiYSXFwtVJlQO5bzZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}