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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6547abd1fa0a54a088107040ddf299d723546c7764c0d449df1cca917f06cec7' 
  AND token = 'PVk7cnbBIiaoO79UNIswZ3HjiRJlTnAHfuvFBhSfB2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}