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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9c6ef3e48e8440ebe6e89862680b3ce7dd4dc767dfb7af993326d7de73cc355' 
  AND token = 'mgSz3kQQAn2leoD3UDVaE1A8nvz/28S2ZbyXJfxuz6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}