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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a65f27a8c74943aab8206de631c53a1134f202e762a5d1bc6721cd9e7a530fa4' 
  AND token = 'vwqBNjbQtFj8T4c0E9pwcPL6iovoAXecqDX8RhaIx3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}