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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de7aa6b5188b062eb2add3a4a6bc504a3ef485a5e083acb110a390a39d67b1d' 
  AND token = 'EfrUOdEy1y+p3B351tyqErLjIsubTIcw8STI2SrXfOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}