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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49bd2406d645a83a8e0f2a89e0a7b2f3737b4134c20ffaff1c5017cb05f32f72' 
  AND token = '0qXHj3Ay1gP+BKFhEKoRmcA+M1s9qRadFchOsTQz1jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}