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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d12df0c2f072f71de52ba8eeb92c659d0ef36a7e65ebb953a0aff13593269a' 
  AND token = 'q0gD3JACtCRCMNIxB8a3EDlTUKmc/pk0AMeXM+qkWmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}