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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d956473f04e2620bc9d12bd96f27ea8fc01dd03f4f6f800da9d3a03a7916d72' 
  AND token = 'lZ3XZk+m6MceDv2FQ40zfv0Ne52GvpaP2kDewuZWnpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}