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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f13b7148c7aabb27a00b3c910f07184ffe7fa744792e03d616a515263bb8d3c9' 
  AND token = '+0jH0t4vbOe7Zkd0nwyoLc4ZE5mAo810Eq6vS0XCgIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}