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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cc89760d589b4b638d29347125fa838a91d23717734a7d5dc191cf49992ff9e' 
  AND token = '16pD4dFZmP+jvLB+apcOYgCYj0C+91vbNDi3FR89aHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}