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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed2a2c6451f3bd561e454a7063f403d35ac294eeeb961f9f1daaf7587b537f59' 
  AND token = 'bIaAxSEeffPmopKc2SXGUmD52rwo+sGejB2geohQcqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}