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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b7c8b8e5eb56f84784cfaabb75f7f9bdd0a655a16ab158d933f6718cd061aa' 
  AND token = 'FUpUsz5+Zv4xMVGxD+575Wf58Zmj/qgFaloujRUNmdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}