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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce1c86bc0c0cb24667f2e735eb173b923a542a5bcb455a73e2ff8d57aae22386' 
  AND token = 'BO0VQKpA4EL+o2piAaQ5meAx7JzRW6M4pjWeJutZmKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}