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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfe2c721db2f1c1167f3609db18c84d2c3e4c797c75159975baabc18b8bd1cf4' 
  AND token = 'MGQkyYW+71vGHyqvzGB74BbihhI0Nc/b0678JY4dAGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}