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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd65ecbf7eab9a6e34e55bce61d66af62826cda19572cf198623ccf4a3147489' 
  AND token = '+vFRDlAxvQTs36Lnixx66Lq/RWJeh07VFDy0oVAqbq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}