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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab572437d98d1b395a5ca74e766709b7d26a1bf24c9d1b160f427852b056e22' 
  AND token = 'wMCkrwJ6GkYsfaFsww6mrQF6m6JjJQDb3YHvOWSX3mU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}