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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4269d561462846ce6cfedd55d4a8ced36d8c0bb4d308ba3e110a6f7b1b204d' 
  AND token = 'do3/E58p5IB4Jo55GDe/Y0nJUI9QZxfqZj3+n6xcCEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}