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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e573f7e570b58e6955aa124ac01221d547ecffb35c63d67e86cae09ea86a778' 
  AND token = 'DxGF0NSUeSDlLUibi1CnysgsdYIJNRiCkPT8f7bzqm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}