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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '010c241cd022eec2416be03019d5ffe45b3f56f4f9120cea49a16fd7dc33be1f' 
  AND token = 's4wyfLSWrQM2oNlMc6X8zybrwktFRF0xEY2W7RKhjSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}