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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea1bc8169d4f4e998385634ff777a1a65747f0ce9778ab7a7d610b0b0b92462' 
  AND token = 'lbFzz/oUf4VFWVBIoe1WKyrGM6PQFLxuNrTfi7Jc0DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}