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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '063c9eaf4aa0f50336c00f82ad4894bd021d4e75b79fbb5645fa6228585a6549' 
  AND token = 'K5BOIFYB4qXXBMyfZopWwEtL0jIRmCgsbd2sgHs/Moo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}