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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f714b2bed46e5407c044a903f66a9d8dfea5710ed44475fc39025af033c1f3' 
  AND token = '8uUkmVk0SzcysN0GoIRSt70QV4+ortXkfFmpfVs8HKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}