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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c286a2bebf003defd7c000fb91c76d2d57797f55b30a1ff0433c49c49929a2b5' 
  AND token = 'oAf8BYN7aE4fedw+SHdy94YqFdJ335TJMArnTX/X4cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}