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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0203cde20381a90860db53a4b9b8d3e4d5cb86711b1157b657989a06db87e3af' 
  AND token = 'BlTy50/zX4K/z0Y4uAiGMmmfERY4EY9YusGNzLGD/R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}