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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a91d8f559938e4557f3c1f0147cd7765b244b2a56d635d2a81566f60b9958cf1' 
  AND token = 'DualziF6rrz0wpTsmedausnfNQYnt0Byh0y28kBRB00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}