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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78bf6aa8421216825993dc8a6fd5e82fe67eb72ffd729c8f9efcd5058f0c9a9a' 
  AND token = '9nMUL+zin7YhTVkghDdimgZcj+75kMr8M/gbxF0iMuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}