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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce803738cea9e77e5eb8c06ad70a446e1aa95cfd1ebb3d6daaba15258749397' 
  AND token = 'd8eQ4SJUvwxUA/naKg3jHAcalZ0VJUfpybypWPb9yeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}