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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c1d7e3b5e80ffdb0db6c43c21e34aa71b8ab18c9042ed6868fd5d4c859f921' 
  AND token = 'HLScZwcFcAsMHcYbjGaxu0rD7G6Cfw7V3c+49YsAtI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}